bibo:abstract
  • We describe here a case of malignant mixed osteogenic tumor of the mammary gland with alveolar carcinomatous appreance. A firm, 2 to 2.5㎝(in diameter) mass under the 5th nipple, showing the structure of extraosseous osteogenic sarcoma, was removed from the left 5th mammary gland of 12-year-old female dog. When investigated under the microscope, the osteoid material undergoing mineralization was surrounded by numerous scattered osteoblasts and a few osteoclastic cells throughout the osteoid tumorous stroma. The osteoid lesions were continuous with hypercellular myoepithelial cells of a very immature character with several mitotic figures. In addition, there were also carcinomatous tubules and alveoli, with invading cells into peripheral stroma, surrounded by myoepithelial cells in the mammary gland. In these lesions, emanating cords of tumor cells appear to be continuous with the myoepithelial cell layer of a duct. The presence of all these cell types suggests the existence of a common malignant origin, the stem cell being differentiated into epithelial carcinomatous and mesenchymal sarcomatous chondral and osteogenic tissues. (rdf:langString) (en)
  • 본 증례는 개의 유선에서 발생한 골형성성의 악성 혼합 유선 종양으로 샘포의 암종성 변화를 동반하고 있다. 종양은 12년령 암캐의 좌측 5번째 유선에서 절제되었으며 직경 2~2.5㎝의 단단한 mass로 절단 시 경도가 높은 골성의 구조를 가지고 있었다. 현미경학적 관찰 시, 골유사 물질이 미네랄 침착되고 있었으며 다수의 골형성 세포와 일부 파골세포가 골생성 종양 기질 전반에 걸쳐서 관찰되었다. 이러한 골유사 병변은 높은 밀집도를 보이는 근상피 세포와 연접하고 있었으며 이러한 세포들은 수 개의 유사분열상을 나타내고 있었다. 이와 더불어, 유선세관과 샘포의 암종성 변화를 보이는 세포들이 인접 기질로 침습하고 있는 모습이 관찰되었고 이것 역시 증가된 근상피 세포들로 둘러싸여 있었다. 본 증례에서 볼 수 있는 이러한 세포들의 출현은 동시 발생된 악성 종양의 형태를 제시할 수 있으며 종양의 기원은 상피 유래의 암종성 조직과 중간엽 유래의 육종성 연골 및 골 조직으로 구별할 수 있겠다. (rdf:langString) (ko)
nlon:biographicalNote
  • Dong-wei Yuan, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Hai-jie Yang, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Hye-rim Lee, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Il-hwa Hong, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Jin-kyu Park, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Jung-youn Han, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Kyu-shik Jeong, Department of Pathology, College of Veterinary Medicine, Kyungpook National University, jeongks (rdf:langString) (knu.ac.kr)
  • Kyung-sook Hong, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Mi-ran Ki, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Moon-jung Goo, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Ok-kyung Hwang, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
  • Sun-hee Do, Department of Clinical Pathology, College of Veterinary Medicine, Konkuk University (xsd:string)
  • Tae-hwan Kim, Department of Pathology, College of Veterinary Medicine, Kyungpook National University (xsd:string)
nlon:classificationNumberOfNLK
  • 470.5 (xsd:string)
nlon:containedIn
dc:creator
  • Goo, Moonjung (xsd:string)
  • Han, Jungyoun (xsd:string)
  • Hong, Ilhwa (xsd:string)
  • Hong, Kyungsook (xsd:string)
  • Hwang, Okkyung (xsd:string)
  • Ki, Miran (xsd:string)
  • Kim, Taehwan (xsd:string)
  • Lee, Hyerim (xsd:string)
  • Park, Jinkyu (xsd:string)
  • Yang, Haijie (xsd:string)
  • Yuan, Dongwei (xsd:string)
  • 도선희 (xsd:string)
  • 정규식 (xsd:string)
dcterms:creator
nlon:datePublished
  • 2021-01-30T23:37:12 (xsd:dateTime)
dcterms:description
  • 개의 유선에서 발생한 혼합성 골육종 및 샘포 상피세포의 전이성 암종 (xsd:string)
bibframe:extent
  • 29 cm (xsd:string)
  • p. 1766-1770 (xsd:string)
dcterms:isPartOf
nlon:issuedYear
  • 2007 (xsd:string)
nlon:itemNumberOfNLK
  • 부641ㅅ (xsd:string)
rdfs:label
  • Mixed osteosarcoma with metastatic alveolar carcinomatous appearance in canine mammary gland tumor / Moon-jung Goo, Il-hwa Hong,Jin-kyu Park,Hai-jie Yang,Dong-wei Yuan,Mi-ran Ki,Hye-rim Lee,Kyung-sook Hong,Jung-youn Han,Ok-kyung Hwang,Tae-hwan Kim,Sun-hee Do,Kyu-shik Jeong (xsd:string)
dcterms:language
dc:subject
  • Canine (xsd:string)
  • Carcinoma (xsd:string)
  • Malignant mammary mixed tumor (xsd:string)
  • Myoepithelial cell (xsd:string)
  • Osteosarcoma (xsd:string)
  • 골형성성 (xsd:string)
  • 악성 종양 (xsd:string)
dcterms:title
  • Mixed osteosarcoma with metastatic alveolar carcinomatous appearance in canine mammary gland tumor (xsd:string)
rdf:type
nlon:volumeOfNLK
  • 17(12) (xsd:string)