bibo:abstract
  • Opuntia ficus-indca(Op) extract has been claimed to have several therapeutic properties in oriental medicine including anti-inflammatory and anti-rheumatoid arthritis effects. Little is known of its effect on the activation of immune cells such as T cells and macrophages. To evaluate the functional effect of Op extract on immune cells, we examined whether Op extract stimulates the proliferation of T cells and the secretion of cytokines including IL-1 beta, IL-6 and tumor necrosis factor-alpha in THP-1 cell lines by RT-PCR. Op extract significantly enhanced the proliferation of T cell clone(D10S). Transcription of cytokines including IL-1 beta, IL-6, and TNF-alpha peaked 6 hrs after exposure to Op extract(100g/ml) in the THP-1 cell line and declined and declined thereafter. In an experiment to test the dose dependency of transcription of cytokines, transcription increased at a dose of 10 g/ml and the maximum expression was obtained at 100 g/ml, 6 hrs after exposure to Op extract. These findings suggest that Op extract is a potent stimulant of immune cells including T cells and macrophages, which acts by stimulating T cell proliferation and upregulating cytokines. These phenomena imply that some edible plants may be beneficial to living animals through the activation of immune functions. (rdf:langString) (en)
dcterms:alternative
  • 손바닥선인장 추출물이 면역계세포의 활성화에 미치는 영향 (xsd:string)
nlon:biographicalNote
  • 김승준, 제주대학교 농과대학 수의학과 (xsd:string)
  • 문창종, 제주대학교 농과대학 수의학과 (xsd:string)
  • 박상준, 한국과학기술원 생명공학연구소 (xsd:string)
  • 신태균, 제주대학교 농과대학 수의학과, 생명과학연구소, shint (rdf:langString) (cheju.cheju.ac.kr)
  • 안미정, 제주대학교 농과대학 수의학과 (xsd:string)
  • 윤도영, 한국과학기술원 생명공학연구소 (xsd:string)
  • 이선주, 생명과학연구소, 자연과학대학 화학과 (xsd:string)
  • 정규식, 한국과학기술원 생명공학연구소 (xsd:string)
  • 최용경, 한국과학기술원 생명공학연구소 (xsd:string)
nlon:classificationNumberOfNLK
  • 470.5 (xsd:string)
nlon:containedIn
dc:creator
  • 김승준 (xsd:string)
  • 문창종 (xsd:string)
  • 박상준 (xsd:string)
  • 신태균 (xsd:string)
  • 안미정 (xsd:string)
  • 윤도영 (xsd:string)
  • 이선주 (xsd:string)
  • 정규식 (xsd:string)
  • 최용경 (xsd:string)
dcterms:creator
nlon:datePublished
  • 2021-01-30T23:37:12 (xsd:dateTime)
dcterms:description
  • Effects of Opuntia ficus-indica extract on immune cell activation (xsd:string)
bibframe:extent
  • 30 cm (xsd:string)
  • p. 362-367 (xsd:string)
  • 삽도 (xsd:string)
dcterms:isPartOf
nlon:issuedYear
  • 2000 (xsd:string)
nlon:itemNumberOfNLK
  • 부641ㅅ (xsd:string)
rdfs:label
  • 손바닥선인장(제주도 기념물 35호) 추출물이 면역계세포의 활성화에 미치는 영향 / 문창종, 김승준,안미정,이선주,정규식,박상준,윤도영,최용경,신태균 (xsd:string)
dcterms:language
dc:subject
  • Activation (xsd:string)
  • Cactus (xsd:string)
  • Cell (xsd:string)
  • Cytokines (xsd:string)
  • Effects (xsd:string)
  • Extract (xsd:string)
  • Ficus-indica (xsd:string)
  • Immune (xsd:string)
  • Lymphocytes (xsd:string)
  • Macrophages (xsd:string)
  • Opuntia ficus-indica (xsd:string)
  • 면역계세포 (xsd:string)
  • 손바닥선인장 (xsd:string)
  • 제주도기념물 (xsd:string)
  • 추출물 (xsd:string)
dcterms:title
  • 손바닥선인장(제주도 기념물 35호) 추출물이 면역계세포의 활성화에 미치는 영향 (xsd:string)
rdf:type
nlon:volumeOfNLK
  • 10(4)-10(6) (xsd:string)